Chemical Synthesis and Characterization of an Equinatoxin II(1–85) Analogue

The chemical synthesis of an 85 residue analogue of the pore-forming protein, Equinatoxin II (EqtII), was achieved. Peptide precursors with over 40 residues were assembled by solid phase synthesis. The EqtII(1–46) fragment was modified to the reactive C-terminal thioester and native chemical ligatio...

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Bibliographic Details
Main Authors: John A. Karas, Marc-Antoine Sani, Frances Separovic
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/22/4/559