Aneuploidy: implications for protein homeostasis and disease
It has long been appreciated that aneuploidy – in which cells possess a karyotype that is not a multiple of the haploid complement – has a substantial impact on human health, but its effects at the subcellular level have only recently become a focus of investigation. Here, we summarize new findings...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2014-01-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/7/1/15 |