Challenges of applying multicellular tumor spheroids in preclinical phase

Challenges of applying multicellular tumor spheroids in preclinical phase

Abstract The three-dimensional (3D) multicellular tumor spheroids (MCTs) model is becoming an essential tool in cancer research as it expresses an intermediate complexity between 2D monolayer models and in vivo solid tumors. MCTs closely resemble in vivo solid tumors in many aspects, such as the het...

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Bibliographic Details
Main Authors: Se Jik Han, Sangwoo Kwon, Kyung Sook Kim
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Cancer Cell International
Subjects:
Multicellular tumor spheroids
Drug screening
Therapeutic efficacy
High-throughput
Microfluidics
Online Access:https://doi.org/10.1186/s12935-021-01853-8

Internet

https://doi.org/10.1186/s12935-021-01853-8

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