The analysis of DMD gene deletions by multiplex PCR in Indonesian DMD/BMD patients: the era of personalized medicine

The analysis of DMD gene deletions by multiplex PCR in Indonesian DMD/BMD patients: the era of personalized medicine

Abstract Objective Duchenne/Becker muscular dystrophy (DMD/BMD) is the most common genetic neuromuscular disease in children, resulting from a defect in the DMD gene located on Xp21.2. The new emerging treatment using exon skipping strategy is tailored to specific mutations, thus molecular diagnosti...

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Bibliographic Details
Main Authors: Kristy Iskandar, Ery Kus Dwianingsih, Linda Pratiwi, Alvin Santoso Kalim, Hasna Mardhiah, Alifiani H. Putranti, Dian K. Nurputra, Agung Triono, Elisabeth S. Herini, Rusdy G. Malueka, Gunadi, Poh San Lai, Sunartini
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Research Notes
Subjects:
Duchenne/Becker muscular dystrophy
DMD gene deletion
Exon skipping therapy
Multiplex PCR
Online Access:http://link.springer.com/article/10.1186/s13104-019-4730-1

Internet

http://link.springer.com/article/10.1186/s13104-019-4730-1

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