Injectable Biomimetic Hydrogels as Tools for Efficient T Cell Expansion and Delivery

Injectable Biomimetic Hydrogels as Tools for Efficient T Cell Expansion and Delivery

Biomaterial-based scaffolds are promising tools for controlled immunomodulation. They can be applied as three dimensional (3D) culture systems in vitro, whereas in vivo they may be used to dictate cellular localization and exert spatiotemporal control over cues presented to the immune system. As suc...

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Bibliographic Details
Main Authors: Jorieke Weiden, Dion Voerman, Yusuf Dölen, Rajat K. Das, Anne van Duffelen, Roel Hammink, Loek J. Eggermont, Alan E. Rowan, Jurjen Tel, Carl G. Figdor
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
adoptive T cell transfer
biomaterial-based scaffold
polyisocyanopeptide hydrogel
3D culture
injectable
T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02798/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02798/full

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