-arginine Supplementation Increased Only Endothelium-Dependent Relaxation in Sprague-Dawley Rats Fed a High-Salt Diet by Enhancing Abdominal Aorta Endothelial Nitric Oxide Synthase Gene Expression

Background: Abnormal vascular reactivity and reduced expression of endothelial nitric oxide synthase ( eNOS ) gene are hallmark of salt-induced hypertension in rats. Although l -arginine is an established vasodilator, the mechanism by which it modulates vascular reactivity in salt-induced hypertensi...

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Bibliographic Details
Main Authors: Abdullahi Adejare, Ahmed Oloyo, Chikodi Anigbogu, Smith Jaja
Format: Article
Language:English
Published: SAGE Publishing 2020-01-01
Series:Clinical Medicine Insights: Cardiology
Online Access:https://doi.org/10.1177/1179546820902843