Complement protein C1q binds soluble antigens of Leishmania major (SLA) via the globular head region, activates the classical pathway, and modulates macrophage immune response

Leishmania species cause a range of moderate to severe diseases affecting cutaneous to visceral regions, thus having a great impact on morbidity and mortality. Leishmania is initially dealt with by human innate immune system immediately after its entry into the body, primarily by the complement syst...

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Bibliographic Details
Main Authors: Ahmed Al-Qahtani, Mohammed N. Al-Ahdal, Saad Alkahtani
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Journal of King Saud University: Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364721000264