Complement protein C1q binds soluble antigens of Leishmania major (SLA) via the globular head region, activates the classical pathway, and modulates macrophage immune response
Leishmania species cause a range of moderate to severe diseases affecting cutaneous to visceral regions, thus having a great impact on morbidity and mortality. Leishmania is initially dealt with by human innate immune system immediately after its entry into the body, primarily by the complement syst...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-05-01
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Series: | Journal of King Saud University: Science |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1018364721000264 |