Evaluation of the antioxidant effects of different histone deacetylase inhibitors (HDACis) on human lens epithelial cells (HLECs) after UVB exposure

Evaluation of the antioxidant effects of different histone deacetylase inhibitors (HDACis) on human lens epithelial cells (HLECs) after UVB exposure

Abstract Background To compare the protective effects of the histone deacetylase inhibitors (HDACis) β-hydroxybutyrate (βOHB), trichostatin A (TSA), suberoylanilide hydroxamic acid (SAHA) and valproic acid (VPA) on human lens epithelial cells(HLECs) following ultraviolet-B (UVB) exposure. Methods HL...

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Bibliographic Details
Main Authors: Xiaodi Qiu, Xianfang Rong, Jin Yang, Yi Lu
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Ophthalmology
Subjects:
Histone deacetylase inhibitors
Lens epithelial cells
Ultraviolet-B exposure
Oxidative damage
Beta hydroxybutyrate
Suberoylanilide hydroxamic acid
Online Access:http://link.springer.com/article/10.1186/s12886-019-1056-7

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http://link.springer.com/article/10.1186/s12886-019-1056-7

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