The Effects of Macrophage Phenotype on Osteogenic Differentiation of MSCs in the Presence of Polyethylene Particles

The Effects of Macrophage Phenotype on Osteogenic Differentiation of MSCs in the Presence of Polyethylene Particles

Wear debris generated from the bearing surfaces of joint arthroplasties leads to acute and chronic inflammation, which is strongly associated with implant failure. Macrophages derived from monocytes recruited to the local tissues have a significant impact on bone healing and regeneration. Macrophage...

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Bibliographic Details
Main Authors: Qi Gao, Claire Rhee, Masahiro Maruyama, Zhong Li, Huaishuang Shen, Ning Zhang, Takeshi Utsunomiya, Elijah Ejun Huang, Zhenyu Yao, Bruce A. Bunnell, Hang Lin, Rocky S. Tuan, Stuart B. Goodman
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomedicines
Subjects:
MSCs
polyethylene particles
macrophage
osteogenic differentiation
Online Access:https://www.mdpi.com/2227-9059/9/5/499

Internet

https://www.mdpi.com/2227-9059/9/5/499

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