Berberine Chloride is an Alphavirus Inhibitor That Targets Nucleocapsid Assembly

The alphavirus chikungunya virus (CHIKV) is an example of an emerging human pathogen with increased and rapid global spread. Although an acute CHIKV infection is rarely fatal, many patients suffer from debilitating chronic arthralgia for years. Antivirals against chikungunya and other alphaviruses h...

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Bibliographic Details
Main Authors: Judy J. Wan, Rebecca S. Brown, Margaret Kielian
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.01382-20