Targeting Streptococcus pneumoniae UDP-glucose pyrophosphorylase (UGPase): in vitro validation of a putative inhibitor
Background: Genome plasticity of Streptococcus pneumoniae is responsible for the reduced efficacy of various antibiotics and capsular polysaccharide based vaccines. Therefore targets independent of capsular types are sought to control the pneumococcal pathogenicity. UcrDP-glucose pyrophosphorylase...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AboutScience Srl
2020-10-01
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| Series: | Drug Target Insights |
| Subjects: | |
| Online Access: | https://journals.aboutscience.eu/index.php/dti/article/view/2103 |