Ndfip1 Prevents Rotenone-Induced Neurotoxicity and Upregulation of α-Synuclein in SH-SY5Y Cells

Ndfip1 Prevents Rotenone-Induced Neurotoxicity and Upregulation of α-Synuclein in SH-SY5Y Cells

Nedd4 family interacting protein 1 (Ndfip1) is an adaptor of Nedd4-family ubiquitin ligases. Experimental results showed that Ndfip1 had a potential neuroprotective effect in neurology diseases. However, the neuroprotective effect and the underlying mechanisms of Ndfip1 in Parkinson's disease (...

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Bibliographic Details
Main Authors: Xin Liu, Le Qu, Na Zhang, Xiaoqi Yu, Zhixin Xiao, Limei Song, Junxia Xie, Huamin Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Parkinson's disease
α-synuclein
Ndfip1
rotenone
dopamine neuron
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2020.613404/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2020.613404/full

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