CXCL8 Associated Dendritic Cell Activation Marker Expression and Recruitment as Indicators of Favorable Outcomes in Colorectal Cancer

CXCL8 Associated Dendritic Cell Activation Marker Expression and Recruitment as Indicators of Favorable Outcomes in Colorectal Cancer

Accumulating evidence suggests that tumor-infiltrating immune cells (TICs) in the tumor microenvironment (TME) serve as promising therapeutic targets. CXCL8 (IL-8) may also be a potential therapeutic target in cancer. CXCL8 is a potent chemotactic factor for neutrophils, myeloid-derived suppressor c...

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Bibliographic Details
Main Authors: Enhao Li, Xiaobao Yang, Yuzhang Du, Guanzheng Wang, David W. Chan, Di Wu, Peiqing Xu, Peihua Ni, Dakang Xu, Yiqun Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
colorectal cancer
CXCL8-CXCR1/2
dendritic cell (DC)
immune profiling
therapeutics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.667177/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.667177/full

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