Selenium-containing protein from selenium-enriched Spirulina platensis antagonizes oxygen glucose deprivation-induced neurotoxicity by inhibiting ROS-mediated oxidative damage through regulating MPTP opening

Selenium-containing protein from selenium-enriched Spirulina platensis antagonizes oxygen glucose deprivation-induced neurotoxicity by inhibiting ROS-mediated oxidative damage through regulating MPTP opening

Context Selenium-containing protein from selenium-enriched Spirulina platensis (Se-SP) (syn. Arthrospira platensis [Microcoleaceae]) showed novel antioxidant activity. However, the protective effect of Se-SP against oxygen glucose deprivation (OGD)-induced neural apoptosis has not been reported yet....

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Bibliographic Details
Main Authors: Xiaojie Song, Lijun Zhang, Xin Hui, Xiangfu Sun, Juntao Yang, Jinlei Wang, Hualian Wu, Xianjun Wang, Zuncheng Zheng, Fengyuan Che, Guojun Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Pharmaceutical Biology
Subjects:
ischaemic brain injury
apoptosis
neurons
mitochondrial dysfunction
Online Access:http://dx.doi.org/10.1080/13880209.2021.1928715

Internet

http://dx.doi.org/10.1080/13880209.2021.1928715

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