Identification of the Prognostic Signatures of Glioma With Different PTEN Status

Identification of the Prognostic Signatures of Glioma With Different PTEN Status

The high-grade glioma is characterized by cell heterogeneity, gene mutations, and poor prognosis. The deletions and mutations of the tumor suppressor gene PTEN (5%-40%) in glioma patients are associated with worse survival and therapeutic resistance. Characterization of unique prognosis molecular si...

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Bibliographic Details
Main Authors: Pei Zhang, Xinyi Meng, Liqun Liu, Shengzhen Li, Yang Li, Sakhawat Ali, Shanhu Li, Jichuan Xiong, Xuefeng Liu, Shouwei Li, Qin Xia, Lei Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
glioma
mutant PTEN
prognostic risk model
risk score
prognostic signature
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.633357/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.633357/full

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