Molecular architecture of a cylindrical self-assembly at human centrosomes

The centrosome is a membraneless organelle composed of two centrioles and an amorphous pericentriolar material but the overall centrosome organizations remains unknown. Here authors show that two scaffold proteins, Cep63 and Cep152, self-assemble into a higher-order cylindrical architecture capable...

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Bibliographic Details
Main Authors: Tae-Sung Kim, Liang Zhang, Jong Il Ahn, Lingjun Meng, Yang Chen, Eunhye Lee, Jeong Kyu Bang, Jung Mi Lim, Rodolfo Ghirlando, Lixin Fan, Yun-Xing Wang, Bo Yeon Kim, Jung-Eun Park, Kyung S. Lee
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08838-2