Historical contingency in the evolution of antibiotic resistance after decades of relaxed selection.

Populations often encounter changed environments that remove selection for the maintenance of particular phenotypic traits. The resulting genetic decay of those traits under relaxed selection reduces an organism's fitness in its prior environment. However, whether and how such decay alters the...

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Bibliographic Details
Main Authors: Kyle J Card, Thomas LaBar, Jasper B Gomez, Richard E Lenski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000397