Denosumab-Induced Immune Hepatitis

Denosumab-Induced Immune Hepatitis

Denosumab–Prolia®, Xgeva® (Amgen) is a fully human antibody to the receptor activator of the nuclear factor-K ligand (RANKL). Hepatotoxicity is extremely rare, with only one reported case of immune origin. We present a second case of hepatotoxicity resulting from an immune reaction to denosumab. A 4...

Full description

Bibliographic Details
Main Authors: Viviana Ostrovsky, Stephen Malnick, Shahar Ish-Shalom, Nadya Ziv Sokolowskaia, Ady Yosepovich, Manuela Neuman
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biomedicines
Subjects:
immune hepatitis
cytokine
denosumab
drug-induced hepatotoxicity
necrosis
nuclear factor-κB (NFκB)
Online Access:https://www.mdpi.com/2227-9059/9/1/76

Internet

https://www.mdpi.com/2227-9059/9/1/76

Similar Items