Caspar controls resistance to Plasmodium falciparum in diverse anopheline species.
Immune responses mounted by the malaria vector Anopheles gambiae are largely regulated by the Toll and Imd (immune deficiency) pathways via the NF-kappaB transcription factors Rel1 and Rel2, which are controlled by the negative regulators Cactus and Caspar, respectively. Rel1- and Rel2-dependent tra...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-03-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2647737?pdf=render |