Caspar controls resistance to Plasmodium falciparum in diverse anopheline species.

Immune responses mounted by the malaria vector Anopheles gambiae are largely regulated by the Toll and Imd (immune deficiency) pathways via the NF-kappaB transcription factors Rel1 and Rel2, which are controlled by the negative regulators Cactus and Caspar, respectively. Rel1- and Rel2-dependent tra...

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Bibliographic Details
Main Authors: Lindsey S Garver, Yuemei Dong, George Dimopoulos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2647737?pdf=render