Dynamic visualization of dendritic cell-antigen interactions in the skin following transcutaneous immunization.

Delivery of vaccines into the skin provides many advantages over traditional parenteral vaccination and is a promising approach due to the abundance of antigen presenting cells (APC) residing in the skin including Langerhans cells (LC) and dermal dendritic cells (DDC). However, the main obstacle for...

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Bibliographic Details
Main Authors: Teerawan Rattanapak, James C Birchall, Katherine Young, Atsuko Kubo, Sayumi Fujimori, Masaru Ishii, Sarah Hook
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3933627?pdf=render