Flecainide-Induced Brugada Syndrome in a Patient With Skeletal Muscle Sodium Channelopathy: A Case Report With Critical Therapeutical Implications and Review of the Literature

Flecainide-Induced Brugada Syndrome in a Patient With Skeletal Muscle Sodium Channelopathy: A Case Report With Critical Therapeutical Implications and Review of the Literature

Skeletal muscle sodium channelopathies are a group of neuromuscular disorders associated with mutations in the SCN4A gene. Because principal sodium channel isoforms expressed in the skeletal muscles and the heart are distinct one from the other, this condition usually spares cardiac functioning. Non...

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Bibliographic Details
Main Authors: Michele Cavalli, Barbara Fossati, Raffaele Vitale, Elisa Brigonzi, Vito A. G. Ricigliano, Lorenzo Saraceno, Rosanna Cardani, Carlo Pappone, Giovanni Meola
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Neurology
Subjects:
sodium skeletal muscle channelopathy
SCN4A
Brugada syndrome
flecainide
mexiletine
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00385/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.00385/full

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