Myosin V functions as a vesicle tether at the plasma membrane to control neurotransmitter release in central synapses

Synaptic vesicle fusion occurs at specialized release sites at the active zone. How refilling of release sites with new vesicles is regulated in central synapses remains poorly understood. Using nanoscale-resolution detection of individual release events in rat hippocampal synapses we found that inh...

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Bibliographic Details
Main Authors: Dario Maschi, Michael W Gramlich, Vitaly A Klyachko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/39440