circ_NRIP1 is oncogenic in malignant development of esophageal squamous cell carcinoma (ESCC) via miR-595/SEMA4D axis and PI3K/AKT pathway

Abstract Background The hsa_circ_0004771 derived from NRIP1 (called circ_NRIP1) is a recently identified oncogenic circRNA. Here, we intended to investigate the role and mechanism of circ_NRIP1 in esophageal squamous cell carcinoma (ESCC), a prevalent and aggressive type of esophageal cancer. Method...

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Bibliographic Details
Main Authors: Shifan Zhou, Zhizhong Guo, Chaofeng Zhou, Yu Zhang, Sai Wang
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-021-01907-x