RNA-Based Detection of Gene Fusions in Formalin-Fixed and Paraffin-Embedded Solid Cancer Samples

RNA-Based Detection of Gene Fusions in Formalin-Fixed and Paraffin-Embedded Solid Cancer Samples

Oncogenic gene fusions are important drivers in many cancer types, including carcinomas, with diagnostic and therapeutic implications. Hence, sensitive and rapid methods for parallel profiling in formalin-fixed and paraffin-embedded (FFPE) specimens are needed. In this study we analyzed gene fusions...

Full description

Bibliographic Details
Main Authors: Martina Kirchner, Olaf Neumann, Anna-Lena Volckmar, Fabian Stögbauer, Michael Allgäuer, Daniel Kazdal, Jan Budczies, Eugen Rempel, Regine Brandt, Suranand Babu Talla, Moritz von Winterfeld, Jonas Leichsenring, Tilmann Bochtler, Alwin Krämer, Christoph Springfeld, Peter Schirmacher, Roland Penzel, Volker Endris, Albrecht Stenzinger
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
gene fusion
targeted therapy
carcinoma
solid tumor
NGS
Online Access:https://www.mdpi.com/2072-6694/11/9/1309

Internet

https://www.mdpi.com/2072-6694/11/9/1309

Similar Items