Construction of a Novel Liver-Targeting Fusion Interferon by Incorporation of a Plasmodium Region I-Plus Peptide

Interferon alpha (IFN α) exerts a multiplicity of biological actions including antiviral, immunomodulatory, and antiproliferative effects. Administration of IFN α is the current treatment for chronic hepatitis B; however, therapy outcome has not been completely satisfactory. The systemic effects of...

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Bibliographic Details
Main Authors: Xuemei Lu, Xiaobao Jin, Yanting Huang, Jie Wang, Juan Shen, Fujiang Chu, Hanfang Mei, Yan Ma, Jiayong Zhu
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/261631