Novel Therapeutic Targets for Hypoxia-Related Cardiovascular Diseases: The Role of HIF-1

Novel Therapeutic Targets for Hypoxia-Related Cardiovascular Diseases: The Role of HIF-1

Insufficient oxygen availability (hypoxia) is a precursor to numerous cardiovascular diseases, including atherosclerosis, pulmonary hypertension, and heart failure. The main site of hypoxic injury in the human body is the mitochondria, where oxygen acts as the final electron acceptor in the process...

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Bibliographic Details
Main Authors: Minxuan Liu, Gina Galli, Yilin Wang, Qiru Fan, Zhenzhong Wang, Xin Wang, Wei Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Physiology
Subjects:
hypoxia
cardiovascular disease
therapeutic target
HIF
myocardial infarction
atherosclerosis
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00774/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00774/full

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