A novel squaramide compound alleviates cognitive deficits through activation of Akt and Erk1/2 in a rat model of vascular dementia

Vascular dementia is the second most common type of dementia, yet no effective treatment for it exists. Akt and Erk1/2 signaling pathways are involved in neuronal survival. It has been reported that bisperoxovanadium (pyridin-2-squaramide), a novel squaramide compound, protects against cerebral isch...

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Bibliographic Details
Main Authors: Meichun Yuan, Hezhong Zhu, Jiajuan Chen, Dan Zhao, Qi Wan, Zhifeng Zhang
Format: Article
Language:English
Published: IMR (Innovative Medical Research) Press Limited 2019-12-01
Series:Journal of Integrative Neuroscience
Subjects:
akt
Online Access: https://jin.imrpress.com/fileup/1757-448X/PDF/1577791321409-1998175397.pdf