Motivational disturbances and effects of L-dopa administration in neurofibromatosis-1 model mice.

Motivational disturbances and effects of L-dopa administration in neurofibromatosis-1 model mice.

Children with neurofibromatosis type 1 (NF1) frequently have cognitive and behavioral deficits. Some of these deficits have been successfully modeled in Nf1 genetically-engineered mice that develop optic gliomas (Nf1 OPG mice). In the current study, we show that abnormal motivational influences affe...

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Bibliographic Details
Main Authors: David F Wozniak, Kelly A Diggs-Andrews, Sara Conyers, Carla M Yuede, Joshua T Dearborn, Jacquelyn A Brown, Kazuhiro Tokuda, Yukitoshi Izumi, Charles F Zorumski, David H Gutmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3677926?pdf=render

Internet

http://europepmc.org/articles/PMC3677926?pdf=render

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