Unraveling the Regulatory G-Quadruplex Puzzle: Lessons From Genome and Transcriptome-Wide Studies

Unraveling the Regulatory G-Quadruplex Puzzle: Lessons From Genome and Transcriptome-Wide Studies

G-quadruplexes (G4s) are among the best-characterized DNA secondary structures and are enriched in regulatory regions, especially promoters, of several prokaryote and eukaryote genomes, indicating a possible role in cis regulation of genes. Many studies have focused on evaluating the impact of speci...

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Bibliographic Details
Main Authors: Subramaniyam Ravichandran, Jin-Hyun Ahn, Kyeong Kyu Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Genetics
Subjects:
G-quadruplex
secondary structure
genome-wide study
transcriptome
transcription
gene expression
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.01002/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.01002/full

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