Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1

Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1

Infection of primary CD4+ T cells with HIV-1 coincides with an increase in glycolysis. We investigated the expression of glucose transporters (GLUT) and glycolytic enzymes in human CD4+ T cells in response to infection with HIV-1. We demonstrate the co-expression of GLUT1, GLUT3, GLUT4, and GLUT6 in...

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Bibliographic Details
Main Authors: Maia Kavanagh Williamson, Naomi Coombes, Florian Juszczak, Marios Athanasopoulos, Mariam B. Khan, Thomas R. Eykyn, Ushani Srenathan, Leonie S. Taams, Julianna Dias Zeidler, Andrea T. Da Poian, Hendrik Huthoff
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Viruses
Subjects:
HIV-1
glycolysis
GLUT1
GLUT3
GLUT4
GLUT6
hexokinase
HK1
T lymphocytes
Online Access:http://www.mdpi.com/1999-4915/10/3/114

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http://www.mdpi.com/1999-4915/10/3/114

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