High Energy Intake Induced Overexpression of Transcription Factors and Its Regulatory Genes Involved in Acceleration of Hepatic Lipogenesis: A Rat Model for Type 2 Diabetes

Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by impaired insulin action and its secretion. The objectives of the present study were to establish an economical and efficient animal model, mimicking pathophysiology of human T2DM to understand probable molecular mechanisms in c...

Full description

Bibliographic Details
Main Authors: Suresh P. Khadke, Aniket A. Kuvalekar, Abhay M. Harsulkar, Nitin Mantri
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/7/4/76