M cell-dependent antigen uptake on follicle-associated epithelium for mucosal immune surveillance
Abstract The follicle-associated epithelium (FAE) covering mucosa-associated lymphoid tissue is distinct from the villous epithelium in cellular composition and functions. Interleukin-22 binding protein (IL-22BP), provided by dendritic cells at the sub-epithelial dome region, inhibits the IL-22-medi...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-09-01
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Series: | Inflammation and Regeneration |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s41232-018-0072-y |