LAMA2 regulates the fate commitment of mesenchymal stem cells via hedgehog signaling

LAMA2 regulates the fate commitment of mesenchymal stem cells via hedgehog signaling

Abstract Background Bone defects are a common clinical condition that has gained an increasing amount of attention in recent years. Causes of bone defect include tumors, inflammation, and fractures. Bone tissue engineering is a novel treatment of bone defect, and human mesenchymal stem cells (hMSCs)...

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Bibliographic Details
Main Authors: Yuan Zhu, Xiao Zhang, Ranli Gu, Xuenan Liu, Siyi Wang, Dandan Xia, Zheng Li, Xiaomin Lian, Ping Zhang, Yunsong Liu, Yongsheng Zhou
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Stem Cell Research & Therapy
Subjects:
LAMA2
Osteogenic differentiation
Human mesenchymal stem cells
Hedgehog signaling
Online Access:http://link.springer.com/article/10.1186/s13287-020-01631-9

Internet

http://link.springer.com/article/10.1186/s13287-020-01631-9

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