Synergistic Protection by Isoquercitrin and Quercetin against Glutamate-Induced Oxidative Cell Death in HT22 Cells via Activating Nrf2 and HO-1 Signaling Pathway: Neuroprotective Principles and Mechanisms of <i>Dendropanax morbifera</i> Leaves

Synergistic Protection by Isoquercitrin and Quercetin against Glutamate-Induced Oxidative Cell Death in HT22 Cells via Activating Nrf2 and HO-1 Signaling Pathway: Neuroprotective Principles and Mechanisms of <i>Dendropanax morbifera</i> Leaves

<i>Dendropanax morbifera</i> leaves (DML) have long been used as traditional medicine to treat diverse symptoms in Korea. Ethyl acetate-soluble extracts of DML (DMLE) rescued HT22 mouse hippocampal neuronal cells from glutamate (Glu)-induced oxidative cell death; however, the protective...

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Bibliographic Details
Main Authors: Hye-Jin Park, Ha-Neul Kim, Chul Young Kim, Min-Duk Seo, Seung-Hoon Baek
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Antioxidants
Subjects:
glutamate-induced oxidative cell death
<i>Dendropanax morbifera</i> leaves
isoquercitrin
quercetin
nuclear factor erythroid 2-related factor 2
heme oxygenase-1
Online Access:https://www.mdpi.com/2076-3921/10/4/554

Internet

https://www.mdpi.com/2076-3921/10/4/554

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