Eef1a2 promotes cell growth, inhibits apoptosis and activates JAK/STAT and AKT signaling in mouse plasmacytomas.

Eef1a2 promotes cell growth, inhibits apoptosis and activates JAK/STAT and AKT signaling in mouse plasmacytomas.

The canonical function of EEF1A2, normally expressed only in muscle, brain, and heart, is in translational elongation, but recent studies suggest a non-canonical function as a proto-oncogene that is overexpressed in a variety of solid tumors including breast and ovary. Transcriptional profiling of a...

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Bibliographic Details
Main Authors: Zhaoyang Li, Chen-Feng Qi, Dong-Mi Shin, Adriana Zingone, Helen J Newbery, Alexander L Kovalchuk, Catherine M Abbott, Herbert C Morse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2873962?pdf=render

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http://europepmc.org/articles/PMC2873962?pdf=render

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