DNA Damage Regulates Translation through β-TRCP Targeting of CReP.

DNA Damage Regulates Translation through β-TRCP Targeting of CReP.

The Skp1-Cul1-F box complex (SCF) associates with any one of a number of F box proteins, which serve as substrate binding adaptors. The human F box protein βTRCP directs the conjugation of ubiquitin to a variety of substrate proteins, leading to the destruction of the substrate by the proteasome. To...

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Bibliographic Details
Main Authors: Theresa B Loveless, Benjamin R Topacio, Ajay A Vashisht, Shastyn Galaang, Katie M Ulrich, Brian D Young, James A Wohlschlegel, David P Toczyski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4474599?pdf=render

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http://europepmc.org/articles/PMC4474599?pdf=render

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