Early functional deficit and microglial disturbances in a mouse model of amyotrophic lateral sclerosis.

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by selective motoneurons degeneration. There is today no clear-cut pathogenesis sequence nor any treatment. However growing evidences are in favor of the involvement, besides neurons, of several partners su...

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Bibliographic Details
Main Authors: Yannick Nicolas Gerber, Jean-Charles Sabourin, Miriam Rabano, Maria d M Vivanco, Florence Evelyne Perrin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338492?pdf=render