Epithelial response to IFN‐γ promotes SARS‐CoV‐2 infection

Epithelial response to IFN‐γ promotes SARS‐CoV‐2 infection

Abstract SARS‐CoV‐2, the agent that causes COVID‐19, invades epithelial cells, including those of the respiratory and gastrointestinal mucosa, using angiotensin‐converting enzyme‐2 (ACE2) as a receptor. Subsequent inflammation can promote rapid virus clearance, but severe cases of COVID‐19 are chara...

Full description

Bibliographic Details
Main Authors: Julian Heuberger, Jakob Trimpert, Daria Vladimirova, Christian Goosmann, Manqiang Lin, Rosa Schmuck, Hans‐Joachim Mollenkopf, Volker Brinkmann, Frank Tacke, Nikolaus Osterrieder, Michael Sigal
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:EMBO Molecular Medicine
Subjects:
ACE2
differentiation
interferon
organoids
SARS‐CoV‐2
Online Access:https://doi.org/10.15252/emmm.202013191

Internet

https://doi.org/10.15252/emmm.202013191

Similar Items