Activation of TRPV1 by Capsaicin or Heat Drives Changes in 2-Acyl Glycerols and N-Acyl Ethanolamines in a Time, Dose, and Temperature Dependent Manner

Activation of TRPV1 by Capsaicin or Heat Drives Changes in 2-Acyl Glycerols and N-Acyl Ethanolamines in a Time, Dose, and Temperature Dependent Manner

Endocannabinoids (eCBs) and transient receptor potential (TRP) channels are associated with thermoregulation; however, there are many gaps in the understanding of how these signaling systems work together in responding to changes in temperature. TRPV1, a calcium-permeable ion channel, is activated b...

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Bibliographic Details
Main Authors: Meera Manchanda, Emma Leishman, Kishan Sangani, Ali Alamri, Heather B. Bradshaw
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
TRPV1
lipidomics
thermoregulation
endocannabinoid
anandamide
2-AG
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.611952/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.611952/full

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