Telomerase efficiently elongates highly transcribing telomeres in human cancer cells.

RNA polymerase II transcribes the physical ends of linear eukaryotic chromosomes into a variety of long non-coding RNA molecules including telomeric repeat-containing RNA (TERRA). Since TERRA discovery, advances have been made in the characterization of TERRA biogenesis and regulation; on the contra...

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Bibliographic Details
Main Authors: Benjamin O Farnung, Catherine M Brun, Rajika Arora, Luca E Lorenzi, Claus M Azzalin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338753?pdf=render