Bias evaluation and reduction in 3D OP-OSEM reconstruction in dynamic equilibrium PET studies with 11C-labeled for binding potential analysis.

Iterative image reconstruction is widely used in positron emission tomography. However, it is known to contribute to quantitation bias and is particularly pronounced during dynamic studies with 11C-labeled radiotracers where count rates become low towards the end of the acquisition. As the strength...

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Bibliographic Details
Main Authors: Cláudia Régio Brambilla, Jürgen Scheins, Ahlam Issa, Lutz Tellmann, Hans Herzog, Elena Rota Kops, N Jon Shah, Irene Neuner, Christoph W Lerche
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0245580