Farnesoid X receptor knockout protects brain against ischemic injury through reducing neuronal apoptosis in mice

Farnesoid X receptor knockout protects brain against ischemic injury through reducing neuronal apoptosis in mice

Abstract Background Farnesoid X receptor (FXR) is a nuclear receptor that plays a critical role in controlling cell apoptosis in diverse diseases. Previous studies have shown that knocking out FXR improved cardiac function by reducing cardiomyocyte apoptosis in myocardial ischemic mice. However, the...

Full description

Bibliographic Details
Main Authors: Hui-Min Shan, Minhua Zang, Qi Zhang, Ru-Bing Shi, Xiao-Jing Shi, Muyassar Mamtilahun, Chang Liu, Long-long Luo, Xiaoying Tian, Zhijun Zhang, Guo-Yuan Yang, Yaohui Tang, Jun Pu, Yongting Wang
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Neuroinflammation
Subjects:
Calcium influx
Farnesoid X receptor
Ischemic stroke
Inflammation
Neuronal apoptosis
Online Access:http://link.springer.com/article/10.1186/s12974-020-01838-w

Internet

http://link.springer.com/article/10.1186/s12974-020-01838-w

Similar Items