HIF1α Regulates IL17 Signaling Pathway Influencing Sensitivity of Taxane-Based Chemotherapy for Breast Cancer

HIF1α Regulates IL17 Signaling Pathway Influencing Sensitivity of Taxane-Based Chemotherapy for Breast Cancer

Hypoxia-induced chemotherapy resistance is the main hindrance for solid tumor treatment. Hypoxia inducible factor-1α (HIF1α), an adaptive gene of hypoxia condition, played an important role in affecting chemotherapy sensitivity for many cancer types and various therapeutic regimens. This study focus...

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Bibliographic Details
Main Authors: Huijuan Dai, Xiaonan Sheng, Yaohui Wang, Liheng Zhou, Yanping Lin, Yueyao Du, Fan Yang, Rui Sha, Jing Peng, Linli Yao, Wenjin Yin, Jinsong Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
hypoxia
hypoxia-inducible factor 1α
breast cancer
chemotherapy
IL-17 pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.729965/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.729965/full

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