Data-based RNA-seq simulations by binomial thinning

Data-based RNA-seq simulations by binomial thinning

Abstract Background With the explosion in the number of methods designed to analyze bulk and single-cell RNA-seq data, there is a growing need for approaches that assess and compare these methods. The usual technique is to compare methods on data simulated according to some theoretical model. Howeve...

Full description

Bibliographic Details
Main Author: David Gerard
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Bioinformatics
Subjects:
RNA-seq
Simulation
Differential expression
Factor analysis
Confounders
Scaling factors
Online Access:http://link.springer.com/article/10.1186/s12859-020-3450-9

Internet

http://link.springer.com/article/10.1186/s12859-020-3450-9

Similar Items