Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses.

BACKGROUND: It is known that primary sequences of enzymes involved in sterol biosynthesis are well conserved in organisms that produce sterols de novo. However, we provide evidence for a preservation of the corresponding genes in two animals unable to synthesize cholesterol (auxotrophs): Drosophila...

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Bibliographic Details
Main Authors: Giovanna Vinci, Xuhua Xia, Reiner A Veitia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2478713?pdf=render