Molecular Subtype May Be More Associated With Prognosis and Chemotherapy Benefit Than Tumor Size in T1N0 Breast Cancer Patients: An Analysis of 2,168 Patients for Possible De-Escalation Treatment

Molecular Subtype May Be More Associated With Prognosis and Chemotherapy Benefit Than Tumor Size in T1N0 Breast Cancer Patients: An Analysis of 2,168 Patients for Possible De-Escalation Treatment

PurposeBreast cancer (BC) patients with T1N0 tumors have relatively favorable clinical outcomes. However, it remains unclear whether molecular subtypes can aide in prognostic prediction for such small, nodal-negative BC cases and guide decision-making about escalating or de-escalating treatments.Pat...

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Bibliographic Details
Main Authors: Siji Zhu, Yafen Li, Weiguo Chen, Xiaochun Fei, Kunwei Shen, Xiaosong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
breast cancer
molecular subtype
prognosis
chemotherapy benefit
de-escalating therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.636266/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.636266/full

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