New Perspectives of S-Adenosylmethionine (SAMe) Applications to Attenuate Fatty Acid-Induced Steatosis and Oxidative Stress in Hepatic and Endothelial Cells

New Perspectives of S-Adenosylmethionine (SAMe) Applications to Attenuate Fatty Acid-Induced Steatosis and Oxidative Stress in Hepatic and Endothelial Cells

S-adenosylmethionine (SAMe) is an endogenous methyl donor derived from ATP and methionine that has pleiotropic functions. Most SAMe is synthetized and consumed in the liver, where it acts as the main methylating agent and in protection against the free radical toxicity. Previous studies have shown t...

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Bibliographic Details
Main Authors: Laura Vergani, Francesca Baldini, Mohamad Khalil, Adriana Voci, Pietro Putignano, Niccolò Miraglia
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
S-adenosylmethionine (SAMe)
non-alcoholic fatty liver disease
atherosclerosis
oxidative stress
steatosis
endothelium dysfunction
Online Access:https://www.mdpi.com/1420-3049/25/18/4237

Internet

https://www.mdpi.com/1420-3049/25/18/4237

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