Central and Peripheral GABAA Receptor Regulation of the Heart Rate Depends on the Conscious State of the Animal

Intuitively one might expect that activation of GABAergic inhibitory neurons results in bradycardia. In conscious animals the opposite effect is however observed. GABAergic neurons in nucleus ambiguus hold the ability to control the activity of the parasympathetic vagus nerve that innervates the hea...

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Bibliographic Details
Main Authors: Bo Hjorth Bentzen, Morten Grunnet
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2011/578273