Population genetic structure and natural selection of Plasmodium falciparum apical membrane antigen-1 in Myanmar isolates

Population genetic structure and natural selection of Plasmodium falciparum apical membrane antigen-1 in Myanmar isolates

Abstract Background Plasmodium falciparum apical membrane antigen-1 (PfAMA-1) is one of leading blood stage malaria vaccine candidates. However, genetic variation and antigenic diversity identified in global PfAMA-1 are major hurdles in the development of an effective vaccine based on this antigen....

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Main Authors:	Jung-Mi Kang, Jinyoung Lee, Mya Moe, Hojong Jun, Hương Giang Lê, Tae Im Kim, Thị Lam Thái, Woon-Mok Sohn, Moe Kyaw Myint, Khin Lin, Ho-Joon Shin, Tong-Soo Kim, Byoung-Kuk Na
Format:	Article
Language:	English
Published:	BMC 2018-02-01
Series:	Malaria Journal
Subjects:	Plasmodium falciparum Apical membrane antigen-1 Genetic diversity Natural selection Myanmar
Online Access:	http://link.springer.com/article/10.1186/s12936-018-2215-7

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